| 1929 | born to Mark D. and Zitta Swanson Eagleton in St. Louis, Missouri |
| 1946 | graduated from St. Louis Country Day School |
| 1948-1949 | served in the United States Navy |
| 1950 | A.B. degree from Amherst College |
| 1953 | LL.B. degree from Harvard Law School |
| 1953-1956 | entered law practice with his father and with the legal department of Anheuser-Busch |
| 1956 | married Barbara Ann Smith |
| 1956-1960 | Circuit Attorney for the city of St. Louis |
| 1959 | son, Terence |
| 1960-1964 | Attorney General of Missouri and the youngest man to ever hold this position |
| 1960 | daughter, Christin |
| 1962 | awarded the Distinguished Service Award by the Clayton Junior Chamber of Commerce |
| 1964-1968 | Lieutenant Governor of Missouri |
| 1964 | named One of Top 100 Young Leaders in the U.S. by LIFE Magazine |
| 1964 | named One of Country's Ten Outstanding Young Men by the St. Louis Junior Chamber of Commerce |
| 1964 | recipient of the Bicentennial Award of Public Service sponsored by the St. Louis Bar Association |
| 1968 | elected to first term in the U.S. Senate (opponent: Congressman Tom Curtis) |
| 1972 | |
| July 14 | Declared winner of the Democratic Party vice presidential balloting at 1:51 A.M. by acclamation at the Democratic National Convention in Miami Beach |
| July 25 | Disclosed at a joint press conference with Sen. George McGovern that he had voluntarily hospitalized himself 3 times between 1960 and 1966 for "nervous exhaustion and fatigue." |
| July 30 | Met with George McGovern and campaign staff |
| July 31 | Withdrew his name from the McGovern-Eagleton ticket at a joint press conference with Sen. McGovern |
| Aug. 5 | R. Sargent Shriver became the new Democratic vice presidential candidate |
| 1987 | columnist for the St. Louis Post-Dispatch University Professor of Public Affairs and Political Science, Washington University, St. Louis partner, Thompson & Mitchell |
| 2007 | died in St. Louis |
| 1972 | Congress and the War Powers, Missouri Law Review, Winter 1972. |
| 1974 | War and Presidential Power: A Chronicle of Congressional Surrender |
| 1975 | On Medicare and Inflation, Senior Power Magazine, 1975. |
| 1987 | Our Constitution and What It Means (McGraw-Hill Book Co.) |
| 1991 | Issues on Business and Government (Prentice-Hall, NY) |